istinctions between Azoxystrobin and kresoxim-methyl

Name

Azoxystrobin

Kresoxim-methyl

Category

Strobilurin

Strobilurin

CAS NO.

131860-33-8

143390-89-0

Molecular formula

C22H17N3O5

C18H19NO4

Molecular weight

403.4

313.35

Physical&Chemical property

Azoxystrobin TC is brown solid with a melting point of 114-116 ° C, pure white crystals, relative density 1.34, vapor pressure 1.1 x 10-7 mPa (20 ℃). Solubility in water 6mg / L (20 ℃), soluble in methanol, toluene, acetone, slightly soluble in n-octanol, hexane, soluble in ethyl acetate, acetonitrile, dichloromethane. The photolysis half-life in aqueous solution is 2 weeks, which is stable to hydrolysis.

The kresoxim-methyl TC is a white powder crystal with a melting point of 87.2-101.7 ℃, a density of 1.258 kg / L (20 ℃), a vapor pressure of 1.3 * 10-6 Pa (25 ℃), and a solubility of 2 g / L (20 ℃).

Toxicity

Acute oral LD50 (male and female) of rats and mice>5000mg/kg, rat oral dosage LD50>2000mg/kg, slightly irritating effect on rabbit skin and eyes. Acute inhalation LC50 (mg/L) in rats: male 0.96, female 0.69. No teratogenic, carcinogenic mutagenic effects. Fish poison LC50 (96h, mg / L) squid 0.47, squid 1.6, to the squid 1.1. Bee LD50>micrograms/only (oral and contact), earthworms LC50 (14d) 283mg/kg.

Acute oral LD50: The acute oral LD50 of male and female rats is greater than 5000mg/kg. Acute percutaneous LD50: The acute percutaneous LD50 of both male and female rats is greater than 2000 mg/kg. It is not irritating to rabbit eyes and skin. The Ames test, the mouse sperm teratogenic test, and the mouse micronucleus test were all negative.

Formulation

25%SC

50%EW

Mechanism of Action

Mitochondrial respiratory inhibitors inhibit mitochondrial respiration by electron transfer in the fine pigment b and c1 bonds. The mitochondria outside the nucleus importantly provide energy (ATP) to the cells through respiration. If the mitochondrial respiration is blocked and ATP cannot be produced, the cells will die.

It is a mitochondrial respiratory inhibitor, that is, by electron transfer between cytochrome b and C1, inhibiting the absorption of mitochondria to undermine ATP, thereby exerting a bactericidal action.

Target objects

Azoxystrobin has a wide range of bactericidal activity, has a good controlling effect on almost all diseases of the fungi (Ascomycetes, Basidiomycetes, Oomycetes and Deuteromycetes) such as powdery mildew, rust, sclerotium, black star, downy mildew, dozens of diseases such as rice blast.

Kresoxim-methyl has good activity against various diseases caused by fungi such as (ascomycetes, basidiomycetes, and oomycetes), such as grape powdery mildew, wheat rust, potato blight, pumpkin blight, rice blast and other diseases. Especially for strawberry powdery mildew, melon powdery mildew, cucumber powdery mildew and pear black spot disease.

Others

Azoxystrobin has protection, therapeutic eradication, permeability and systemic activity. Can be used for stem and leaf spray, seed & soil treatment. It has a good control effect on grape powdery mildew and apple scab diseases.

Kresoxim-methyl not only has a broad spectrum of bactericidal activity, but also has a good protective and therapeutic effect. No cross-resistance with other commonly used fungicides and has a longer shelf life than conventional fungicides. highly selective, safe for crops, humans and animals, and beneficial to the environment, and has no pollution to the environment.